Method of administration

Buvidal is intended for subcutaneous administration only.

It should be injected slowly and completely into the subcutaneous tissue of different areas (buttock, thigh, abdomen or upper arm), provided there is enough subcutaneous tissue. Each area can have multiple injection sites.

Injection sites should be rotated for both weekly and monthly injections. A minimum of 8 weeks should be left before re-injecting a previously used injection site with the weekly dose.

There is no clinical data supporting reinjection of the monthly dose into the same site. This is unlikely to be a safety concern.

The decision to reinject at the same site should also be guided by the attending physicians´ clinical judgement.

The administered dose should be given as a single injection and not as divided doses. The dose must not be administered intravascularly (intravenously), intramuscularly or intradermally.

Buvidal injection technique

Before administration

Safety syringe parts (see Figure 1):

Please note that the smallest injection volume is barely visible in the viewing window as the spring of the safety device is “covering” part of the glass cylinder close to the needle.


  • Take the syringe out of the cardboard box: pick up the syringe by the syringe guard body.
  • While holding the syringe by the needle shield, insert the plunger rod into the plunger stopper by gently rotating the plunger rod clockwise until secured (see Figure 2).
  • Inspect the safety syringe closely:
    • Do not use the safety syringe after the expiration date shown on the cardboard box or on the syringe label.
    • A small air bubble may be seen, which is normal.
    • The liquid should be clear. Do not use the safety syringe if the liquid contains visible particles or is cloudy.
  • Choose the injection site. Injections should be rotated between sites in the buttock, thigh, abdomen, or upper arm (see Figure 3) with a minimum of 8 weeks before re-injecting a previously used injection site. Injections on the waistline or within 5 cm of the navel should be avoided.
  • Put on gloves and clean the injection site with a circular motion using an alcohol wipe (not provided in the pack). Do not touch the cleaned area again before injecting.
  • While holding the safety syringe by the syringe guard body as shown (see Figure 4), carefully pull the needle shield straight off. Immediately dispose of the needle shield (never try to recap the needle). A drop of liquid may be seen at the end of the needle. This is normal.
  • Pinch the skin at the injection site between the thumb and finger as shown (see Figure 5).
  • Hold the safety syringe as shown and insert the needle at an angle of approximately 90° (see Figure 5). Push the needle all the way in.
  • While holding the syringe as shown (see Figure 6), slowly depress the plunger until the plunger head latches between the syringe guard wings and all the solution is injected.
  • Gently pull the needle out of the skin. It is recommended that the plunger is kept fully depressed while the needle is carefully lifted straight out from the injection site (see Figure 7).
  • As soon as the needle has been completely removed from the skin, slowly take the thumb off the plunger and allow the syringe guard to automatically cover the exposed needle (see Figure 8). There may be a small amount of blood at the injection site, if required wipe with a cotton ball or gauze.

Disposing of the syringe

Any unused medicinal product or waste material should be disposed of in accordance with local requirements.

Important information

  • The product must not be used if the safety syringe is broken or the packaging is damaged.
  • The needle shield of the syringe may contain rubber latex that may cause allergic reactions in latex sensitive individuals.
  • Handle the safety syringe carefully to avoid a needle stick. The safety syringe includes a needle protection safety device that will activate at the end of the injection. Do not uncap the safety syringe until you are ready to inject. Once uncapped, never try to recap the needle.
  • Dispose of the used safety syringe right away after use. Do not re-use the safety syringe.

Contact us


Privacy notice

Terms of use

© 2021 Camurus AB. All rights reserved | INT-BUV-2100026 | Date of preparation: June 2021 | Based on the EU SmPC May 2021